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Sleep Apnea Was Just Linked To A Higher Risk Of Dementia—Especially For Women

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The Link Between Obstructive Sleep Apnea and Increased Dementia Risk in Women

The Link Between Obstructive Sleep Apnea and Increased Dementia Risk in Women

Obstructive sleep apnea (OSA) is a prevalent condition that affects approximately 39 million adults in the United States. Left untreated, it poses serious health risks, including complications related to heart, kidney, and metabolic health. Recent research has revealed another alarming association: an increased risk of dementia, particularly for women.

Understanding the Study

A recent study published in SLEEP Advances examined survey and cognitive screening data from over 18,500 adults aged 50 and above. The findings indicated that individuals with obstructive sleep apnea are up to five percent more likely to be diagnosed with dementia later on. This correlation remained significant even after controlling for other dementia risk factors like race and education.

Remarkably, women across all age groups with known or suspected sleep apnea had a heightened likelihood of developing dementia compared to their male counterparts. The researchers emphasized that sleep apnea represents a modifiable yet often overlooked risk factor for dementia onset.

Why Sleep Apnea is Linked to Dementia

While the study did not explicitly define the mechanisms behind this association, researchers propose several theories. Dr. W. Christopher Winter, a neurologist and sleep medicine physician, explained that sleep apnea disrupts sleep architecture. This disruption interferes with the brain’s glymphatic system, responsible for eliminating waste products during sleep. Additionally, sleep apnea can lead to inflammation, elevated blood pressure, and increased vascular risks, all of which are significant contributors to dementia.

Dr. David Merrill, a geriatric psychiatrist, noted that poor sleep perpetuates acute and chronic changes in brain function. A good night’s sleep enables the brain to repair and restore itself, and sleep apnea compromises this restorative process.

Greater Risks in Women

The reasons for the pronounced association between sleep apnea and dementia in women remain unclear, necessitating further research. Potential factors include hormonal influences or women’s heightened sensitivity to sleep apnea’s cardiovascular effects. Additionally, there may be discrepancies in diagnostic rates of sleep apnea between genders.

Treatment and Its Impact on Dementia Risk

Interventions for sleep apnea include lifestyle changes, positional therapy, and the use of Continuous Positive Airway Pressure (CPAP) machines. Dr. Winter affirmed that effectively treating sleep apnea can significantly reduce the future risk of dementia. Although individuals with treated sleep apnea may still have a slightly elevated baseline risk, their chances of dementia are considerably diminished compared to those who ignore their symptoms.

Strategies to Reduce Dementia Risk

While the precise causes of dementia are multifaceted and not exclusive to sleep apnea, healthcare professionals recommend several measures to lower overall dementia risk, including:

  • Staying physically active
  • Managing diabetes
  • Controlling blood pressure
  • Addressing hearing loss
  • Reducing alcohol consumption and avoiding smoking

Conclusion

As research continues to unfold, the association between obstructive sleep apnea and dementia underscores the importance of treatment and early intervention. Understanding and addressing sleep apnea not only enhances overall well-being but could also play a critical role in lowering the risk of dementia, particularly among women.



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